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January 19th 2023

Why batch mode molecular weight determination still matters

Why batch mode molecular weight determination still matters.

Batchmode determination of molecular weight remains a tried and trusted method in many polymer and protein labs despite the availability of newer chromatographic methods. The reason for this is that batch measurements, like those performed with a research grade goniometer system, are far more accurate than chromatographic methods which can be impacted by variability in a larger number of parameters.

Learn more.


January 12th 2023

Chemical reactions – the importance of accurate flow measurement

Flowmeter FAQ 1:

Q: My #liquidchromatographyflowmeter offers 5 possible integration times, which should I select?

A: For most HPLC or GPC/SEC applications, selecting 1172 msec #integrationtime ensures that any pump pulsation or transient flow spikes will have minimal impact on your measurement. Using this setting will provide an accurate measurement of the average flow rate providing you with a reliable evaluation of your system’s performance. Shorter integration times should be selected if you are looking to troubleshoot a problem with your liquid chromatography system as it allows you to pinpoint the source of flow fluctuation.

Learn more.


January 5th 2023

TESTA goes greener

TESTA goes greener

To further enhance the 'green credentials' of our popular Flowmeter range we have introduced new recyclable packaging for these popular products and removed all previously used plastic bags. Now you can undertake real time flowmonitoring of your liquid chromatograph or flow chemistry reagent pump and still be kind to the environment.

Latest news.


December 21st 2022

Happy Holidays

Happy Holidays

Christmas is fast-approaching, and we hope that you will be able to take some well-earned time off to spend with your family and friends. We would like to take this opportunity to offer our thanks, and best wishes for 2023, to the most important people to TESTA Analytical – our customers, suppliers, and employees.

Latest news


December 15th 2022

Removing inter-detector delay improves triple detection GPC/SEC

Removing inter-detector delay improves triple detection GPC/SEC.

Triple detection GPC/SEC is a tried and trusted technique for determining structural information about investigated samples, and to do this without the need of any calibration or reference material. Often, structure information can be expressed in terms of the Mark-Howink coefficients Alpha and K, which allow rapid comparison of structural properties of materials without the need for branching calculations which tend to be tedious and can be prone to error. However, the exactness of any structure related evaluation puts high demands on the accuracy of the measurements and especially on the set-up of GPC/SEC detectors to minimize inter-detector volume delay. Our COMBO #DRIViscometerdetector, with its unique zero delay design, is the perfect match for any MALS detector creating a triple detection GPC/SEC system of unmatched performance.

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December 7th 2022

Chemical reactions – the importance of accurate flow measurement

Continuous monitoring vs scheduled validation of HPLC Pump flow.

To ensure the quality and reliability of your HPLC system data it is important to validate the performance of your HPLC Pump on a regular basis. Some labs choose to do this using scheduled pump flow measurements maybe once a month. However, this type of intermittent performance validation offers only a single data point, and many separations might be run between validations before an error condition is revealed. Continuous monitoring, which is very easily realized using a TESTA Liquid Chromatography Flowmeter, allows continuous determination of flow therefore providing validation of each and every separation run with your HPLC system. This non-invasive device is proven to offer a highly reliable quality assessment of real time liquid flowdata from any HPLC, UHPLC, Ion-Chromatography or GPC/SEC system.

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December 1st 2022

The importance of understanding pump flow

The importance of understanding pump flow

Pumps are one of the most common tools enabling liquids to be moved, delivered, and pushed through a separation column, supplied as a dose or transferred from one container to another. A recently published #technicalarticle written by TESTA Analytical demonstrates and discusses the factors that can affect the flow of liquid delivered by pumps used in a laboratory for analytical purposes such as chromatography, and for lab-level flow chemistry applications.

Read article.


November 24th 2022

Exceptional Refractive Index detector stability

4 reasons why you should use a Solvent Line Monitor

If you are a user of HPLC, uHPLC or GPC/SEC equipment then our affordably priced Solvent Line Monitor device can offer you some great benefits by automatically monitoring:
• To shut down your pump if a solvent reservoir runs dry.
• To stop your system if piston pump backflush is detected.
• To detect cavitation of solvent in pump tubing.
• To alert you when bubbles build up in your pump tubing.
The Solvent Line Monitor not only ensures reliable results but it also takes care of your chromatography systems freeing you to perform other tasks.

Learn More


November 17th 2022

Advanced light scattering consultancy & training.

Advanced light scattering consultancy & training.

Our Managing Director - Carlo Dessy has been invited to the King Abdullah University of Science and Technology (KAUST) in Saudi Arabia to perform an upgrade on their 200SM light scattering goniometer system. During his visit – Carlo will also provide expert advice and training covering all aspects of advanced static and dynamic light scattering techniques for challenging research applications. Founded in 2009, KAUST is renowned for advancing science and technology through distinctive and collaborative research.

Learn more.


November 10th 2022

Chemical reactions – the importance of accurate flow measurement

Chemical reactions – the importance of accurate flow measurement

Accurately measuring the rate of addition of liquid reagents is a critical consideration for many laboratories undertaking batch or flow chemistry reactions. When dispensing expensive chemicals or other fluids into a reaction, labs must ensure the right amounts are added as part of quality control. Without accurate flow measurement, too much or too little chemical can be injected into a reaction, resulting in adverse outcomes, expensive reagent overuse and safety issues. In fact, inaccurate flow measurement can mean the difference between profits and lost revenue.

Learn more.


November 3rd 2022

Why is precise dn/dc measurement important?

Why is precise dn/dc measurement important?

Light scattering is a trusted detection method for measuring molecular weight and therefore a widely used tool for analyzing biopolymers, polymers and proteins by GPC/SEC. One of the most important parameters to ensure top quality light scattering data is the refractive index increment (dn/dc). Accurately determining the dn/dc value is vital because it is the link that translates raw refractive index data into sample concentration. The most accurate method of determining dn/dc is to use a stand-alone batch instrument, such as our HK series differential refractometer, and to take measurements at different concentrations.

Learn More.


October 27th 2022

Exceptional Refractive Index detector stability

Exceptional Refractive Index detector stability

Recent technical developments on our popular Differential Refractive Index detector (DRI) now enable impressive stability right after power up. Unlike other DRI’s on the market, the HK Series DRI reaches perfect stability and drift close to zero in under 10 minutes after being switched on, independent of flow. Why wait for top quality HPLC or GPC/SEC refractive index detection results?

Learn More.


October 19th 2022

TESTA launch flowmeter calibration services

TESTA launch flowmeter calibration services

Having proof of the precision and accuracy of any measurement device is essential to being able to demonstrate the reliability and repeatability of the data it produces. In applications including liquid chromatography and flow chemistry where stable and precise flow are directly related to the reliability of results or quality of product – having a certified, calibrated flow measurement device is required by many users especially those working in regulated industries. In response to this need, we have introduced a calibration and validation service for all users who might need or wish to have their TESTA flowmeter checked or calibrated with a specific solvent. This annual service is available across Europe and is performed at the manufacturer facility, with fast response time and competitive service fees.

Learn more.


October 12th 2022

How to improve your polymer branching determination

How to improve your polymer branching determination

Determination of polymer branching with GPC/SEC is often a challenging task. The requirements regarding accuracy and precision of measured data are more demanding than those for simple molecular weight determination. This challenge places specific requirements on your choice of the required GPC/SEC detectors - DRI, MALS, and viscometer. The typical connection of these three detectors in series leads to an improvement in branching determination results. However, as the delay volume between detectors cannot be optimized, this limits the quality of achievable results. Through development of a combined DRI Viscometer, the HK Combo in which the DRI cell is integral component of the viscometer bridge, TESTA has overcome most of the described problems through its unique “Zero-Delay” design. Used in combination with a MALS, this elegant solution leads to enhanced sensitivity in the lower molecular weight range and to much higher #reliabilityofresults.

Learn more about the HK Combo


October 5th 2022

Reliable, Quantitative LC/MS

Reliable, Quantitative LC/MS

Our new AB-40004 microflowmeter (µFlowmeter) is an affordable non invasive device optimised to provide continuous high precision measurement of low volume liquid flows that may be split off for analysis from chromatography systems. Fully compatible with all organic and aqueous chromatography solvents, the AB-40004 µFlowmeter is the perfect tool for precise measurement of liquid flow to ensure reliable, quantitative HPLC / mass spectrometry (LC/MS) measurements.

Learn more


September 28th 2022

Coreolis versus real time flow monitoring

Coreolis versus real time flow monitoring

We are sometimes asked about the benefits of TESTA’s liquid chromatography flowmeter compared to Coreolis flow devices? Critically our unit offers immediate reading while Coreolis devices typically need 30 seconds or more to stabilise before readings can be considered 'ok'. This long- and variable-time lag with Coreolis devices introduces uncertainty into trusting your flow measurements. Additionally, the time resolution of the TESTA flowmeter is forty-five milliseconds compared to several seconds with a Coreolis device. The low resolution of Coreolis devices means they not suitable for troubleshooting flow problems with your chromatography system which are typically fast processes.

Download ‘real time monitoring’ tech note.


September 21st 2022

TESTA doubles production capacity

Key tools for the Semiconductor industry …. Part 2

Detection of air bubbles in semiconductor manufacturing processes can negatively affect your product quality and production efficiency. For example, the presence of air bubbles in the photoresist used in photo lithography can result in defective wafers. In addition, the presence of air bubbles in semiconductor wafer manufacturing process coolant may lead to an interruption of the process and lower production efficiency. Designed to help solve such problems, the Solvent Line Monitor (SLM) is a programmable, high sensitivity device for automated detection of gas bubbles in liquids.

Learn more.


September14th 2022

Automated detection of empty HPLC system solvent reservoirs.

Automated detection of empty HPLC system solvent reservoirs

While many modern HPLC and uHPLC instruments offer facility to detect empty solvent reservoirs, they also require human intervention to inform the system about the status of solvent feed bottles. Dedicating a technician to such a mundane task is poor use of resources and limits HPLC system running time to standard lab hours.

Learn how to resolve this problem


September 7th 2022

Key tools for the Semiconductor industry …. Part 1

Key tools for the Semiconductor industry... Part 1

Cleaning liquids play a key role in the production of #semiconductor wafers. #Preciseflowmeasurement is critical to ensure that exactly the right amount of #cleaningsolution is used. Too little and the cleaning process must be repeated or worse you risk valuable wafers having to be discarded. Likewise, using too much cleaning solution increases your costs. Built from inert materials, our #LiquidFlowmeter is the perfect real-time non-invasive measurement for this critical application.

Learn more


August 31st 2022

No1 in Precision Liquid Flow Measurement

No1 in Precision Liquid Flow Measurement

Are you looking to #measureliquidflow in #realtime from an analytical or preparative chromatography system, #massspectrometer or #peristalticpump? Then look no further.

Click here to learn more.


August 24th 2022

TESTA doubles production capacity

TESTA doubles production capacity

To ensure that everyone can continue to enjoy quick delivery of all our most popular GPC/SEC, HPLC products – TESTA has doubled its production capacity and significantly invested in key component #stock. This investment follows a significant increase in sales received for our liquid chromatography flowmeter and differential refractive index detectors in particular during 2022.

Learn more.


August 17th 2022

Software assists precise flow monitoring

Software assists precise flow monitoring

Version 1.4 of our flowmeter software enables data to be acquired and visualized in real-time. Operating in conjunction with our Liquid Chromatography flowmeter the easy-to-use PC software app enables fast, simple experimental set-up and provides full control of device settings including integration time and calibration factor. The app will also report average and min/max values of the measured flow. All flow data is automatically stored in files that can be processed later using almost any commercial data analysis package.

Learn more


August 10th 2022

TESTA Co-author Conference Paper

TESTA Co-author Conference Paper

In July 2022, the 3rd International Conference on Ionizing Processes (ICIP) focused on the fundamental chemical, physical and biological science of #ionizingradiation and groundbreaking applications in areas such as nuclear energy, materials synthesis and medicine. At this international meeting, Professor Slawomir Kadlubowski from the renowned #LodzUniversity of Technology (Poland), in conjunction with our own Carlo Dessy, gave a popular presentation – ‘Radiation-induced #synthesisofnanogels’ where the synthesized product property data shown was from a TESTA Analytical triple detection Gel Permeation Chromatography system.

Read presentation (in full)
Learn more about TESTA GPC/SEC systems


July 20th 2022

Non-contact bioprocess flow monitoring

Non-contact bioprocess flow monitoring

Based upon proprietary non-contact technology, our liquid flowmeter is the perfect tool for upstream and downstream monitoring of bioprocess flow. Compact in size, and conveniently powered via a USB connection, our liquid flowmeter uses a thermal flow sensor that is extremely #accurate, #sensitive, and high-resolution. As the sensor does not interfere with the measurement it can operate over a wide dynamic range and has been demonstrated to be the perfect #realtimeflowmonitoring tool for a growing range of bioprocess applications.

Learn more.


July 13th 2022

Verification of Zeta Potential Performance

Verification of Zeta Potential Performance

Zeta potential is the technique of choice for a growing range of application including analysis of printing inks, meeting water purity safety standards, providing an indication of #suspensionstability and characterizing proteins for effective drug delivery. But are your zeta potential measurements accurate? Our latest guide walks you through a zeta potential validation process from start to finish.

Download guide


July 6th 2022

High sensitivity device for detecting gas bubbles

Refractive index detector kits for HPLC

Operating from room temperature up to 80°C, our unique Differential Refractive Index (DRI) detector kit offers superb #baselinestability and #highsensitivity enhancing results from your #HPLC system. The flexibility of this DRI detector design has also enabled TESTA to design and supply optimised OEM versions for #uHPLC and HPLC system manufacturers looking to generate great results from a wide range of applications.

Learn more (end users)
Learn more (OEM enquiries)


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